Hello, Frank Indiviglio here. Central and South American frogs of the family Dendrobatidae secrete virulent skin toxins (histrionicotoxins, batrachotoxins and others) when disturbed.  Many people believe that the toxins of many species of Poison Frogs, known also as “Poison Arrow Frogs” and “Dart Poison Frogs”, were once used to coat darts and arrows used in hunting and warfare.  Actually, this is not the case – but the actual facts are no less interesting.